Does Vaping Affect Fertility? Understanding the Risks
- Olga Pysana
- Mar 26
- 6 min read

Once, a couple contacted me asking if vaping and fertility problems could be connected. She'd been vaping for 3 years. He'd picked up e-cigarettes last year. After 18 months of trying for a baby - nothing.
They're not alone.
I've seen this question pop up more and more in my consultations. While helping over 250 families build their families through surrogacy, I've noticed a pattern: younger clients, seemingly healthy, struggling to conceive. The common thread? Many use e-cigarettes.
"But it's not like smoking," they tell me. "It's just vapour."
Is it though?
The truth about vaping and fertility isn't what most want to hear. Those fruity clouds contain chemicals that researchers are increasingly linking to reproductive problems. Not as bad as cigarettes? Maybe. Harmless? Definitely not.
For some of my clients, surrogacy becomes the path forward after years of unexplained fertility struggles. It's brilliant for creating families, but let's be honest - it's also complex, expensive, and emotionally demanding. I'd much rather help people protect their fertility before it becomes compromised.
The most frustrating part? Some fertility problems from vaping might be preventable. But first, we need to understand what e-cigarettes are actually doing to our bodies.
How Vaping Affects Male Fertility

When Tom (not his real name) came to me last spring, he was baffled. At 32, healthy and fit, he'd just received devastating news: his sperm count was extremely low. The fertility specialist had asked about smoking. "I don't smoke," he'd said proudly. "I switched to vaping three years ago."
The doctor's response? "That might be your problem."
This is what men need to understand: Does vaping affect sperm? Research indicates it might, and here's why:
Nicotine itself reduces blood flow throughout the body - that's been established for decades. A 2020 study in the Journal of Endocrinological Investigation found this reduced blood flow extends to testicular tissue, where good circulation is crucial for sperm production.
But what about those flavourings? Here's the actual science: When heated in e-cigarettes, common flavour chemicals like diacetyl and pentanedione break down and create harmful compounds. Research published in Scientific Reports showed these chemicals can trigger oxidative stress in cells - basically causing cellular damage. For sperm, which are incredibly fragile, this oxidative stress can impair both their movement and their DNA integrity.
The relationship between vaping and sperm count is still being studied, but a 2019 analysis in Andrologia found men who vaped had, on average, 17% fewer sperm per milliliter than non-vapers. Not as dramatic as cigarette smoking's impact (which was 29% in the same study), but still concerning.
For Tom and his partner, international surrogacy became their path to parenthood. Before the current war there, Surrogacy in Ukraine offered fertility care that many of my clients found accessible. Although circumstances have changed, the point remains - men are seeking fertility solutions for problems that research suggests might be connected to vaping.
What's encouraging is that male fertility can improve. Since new sperm develop roughly every 74 days, positive changes can show results within 2-3 months. That's what Tom's doctor told him, and it's what reproductive specialists confirm.
If you're vaping and planning to have children someday, these studies suggest it's worth reconsidering that habit.
Impact of Vaping on Female Fertility

I met with a client last month who had been vaping for years. "No one ever mentioned it could affect my chances of having a baby," she told me. She's not alone in this confusion about vaping and fertility.
The truth is, scientists are still gathering evidence, but what they've found so far gives us reason to be cautious.
Let's look at what research actually shows: A 2020 study in the Journal of the Endocrine Society found that women who vape had measurable changes in their hormone levels compared to non-vapers. Specifically, they showed altered levels of anti-Müllerian hormone (AMH), which doctors use to assess ovarian reserve - essentially, how many eggs a woman has left.
The nicotine in e-cigarettes is particularly concerning. Research published in the American Journal of Physiology has confirmed that nicotine reduces blood flow to reproductive organs. For ovaries, this matters tremendously - they need robust blood supply to function properly and nurture developing eggs. This reduced blood flow can potentially affect both egg quality and quantity.
Beyond nicotine, the heating process in e-cigarettes creates compounds that weren't in the original liquid. A 2018 study in Environmental Health Perspectives identified that these thermal breakdown products can trigger inflammatory responses in the body. For fertility, inflammation in reproductive tissues can interfere with hormone function and potentially impair implantation.
For women struggling with fertility who are exploring alternatives, Surrogacy in the UK operates under specific guidelines. Unlike commercial surrogacy in some countries, UK arrangements are altruistic - surrogates can be reimbursed for reasonable expenses but cannot be paid for carrying the baby. The legal process requires a parental order after birth to transfer parenthood from the surrogate to the intended parents.
Encouragingly, reproductive specialists note that reducing exposure to vaping may help improve fertility factors over time. The body has remarkable healing capacity, and removing potential reproductive toxins gives your reproductive system its best chance to function optimally.
If you're trying to conceive and currently vape, having an honest conversation with your doctor about all lifestyle factors, including vaping, is an important step toward addressing any barriers to fertility.
Thanks for the feedback. I'll continue with the next section on nicotine and fertility, including some subsections and lists for better readability.
Nicotine and Its Role in Fertility
"I've switched to nicotine-free vape juice - so I should be fine, right?" This is a question I hear regularly from clients hoping to protect their fertility. Unfortunately, the answer isn't that straightforward.
Nicotine itself is one of the most studied compounds in relation to vaping and fertility, and the evidence points to several specific concerns:
How Nicotine Damages Male Fertility
Research published in the Journal of Assisted Reproduction and Genetics shows nicotine affects men's fertility in several ways:
Reduced Sperm Count: Studies have found that men exposed to nicotine typically produce fewer sperm overall. Research in Reproductive Biology and Endocrinology documented an average 16% reduction in sperm concentration among nicotine users.
Impaired Sperm Movement: Nicotine interferes with the energy-producing parts of sperm cells (mitochondria), making them less able to swim efficiently. A 2019 study in Andrologia found that sperm from nicotine-exposed men showed significantly reduced forward movement.
DNA Fragmentation: Perhaps most concerning, nicotine exposure increases DNA damage in sperm. Research in the European Journal of Endocrinology found that this damage can affect embryo development even if fertilisation occurs.
Does vaping affect sperm as much as smoking? Not quite as severely, but the impact is still significant. A comparative study found smoking reduced sperm counts by approximately 29%, while vaping showed a 15-20% reduction - better, but hardly reassuring.
How Nicotine Impacts Female Fertility
For women, nicotine's effects on fertility include:
Disrupted Hormone Production: Nicotine interferes with the hypothalamic-pituitary-ovarian axis, the system that regulates reproductive hormones. This can lead to irregular ovulation and menstrual cycles.
Reduced Ovarian Reserve: Research in the Journal of Ovarian Research documented that nicotine exposure accelerates the loss of primordial follicles - essentially depleting egg supply faster.
Impaired Embryo Implantation: Studies published in Human Reproduction found nicotine reduces endometrial receptivity, making it harder for embryos to implant and establish pregnancy.
Improving Egg Quality After Nicotine Exposure
For women concerned about how to improve egg quality after using nicotine products, there are evidence-based approaches:
Complete Cessation: The single most effective step is stopping nicotine use entirely. Research suggests improvements can begin within 3 months.
Antioxidant Support: Studies in Reproductive Sciences show that antioxidant supplements like CoQ10 (600mg daily) and Vitamin E (400 IU daily) may help counteract some nicotine-induced oxidative damage.
Improved Blood Flow: Regular moderate exercise increases blood flow to reproductive organs. Research in Fertility and Sterility found women who exercised moderately (150 minutes weekly) showed improved ovarian function markers.
Mediterranean Diet: A 2019 study in Human Reproduction found that women following a Mediterranean diet (rich in vegetables, fruits, whole grains, olive oil, and fish) had better markers of egg quality regardless of previous exposures.
The most important thing to understand is that vaping and fertility problems aren't just about nicotine. Even nicotine-free e-liquids contain compounds that, when heated, may affect reproductive health. The safest approach for anyone hoping to conceive is avoiding all vaping products, regardless of nicotine content.

What You Can Do to Protect Your Fertility
"Is it too late?" That's what clients ask when they learn how vaping and fertility connect. Good news - your body can recover with the right steps:
Quit vaping completely - Fertility markers can improve within 3-6 months after stopping. NHS Stop Smoking Service offers specific support for vaping cessation.
Improve your diet - Research shows Mediterranean-style eating (vegetables, fruits, fish, olive oil) benefits both egg and sperm health.
Target key nutrients - For those concerned about the vaping effect on sperm concerns, foods rich in zinc and antioxidants help repair damage. Women benefit from foods that improve circulation to reproductive organs.
Manage stress - High cortisol levels directly interfere with reproductive hormones. One study found stressed women took 29% longer to conceive.
Know when to seek help - If you've been trying for a baby for a year without success (six months if you're over 35), see a fertility specialist. Be honest about your vaping history.
For those with severe fertility issues, understanding the Pros and Cons of Surrogacy becomes important. While surrogacy offers a path to biological parenthood, it involves complex emotional, legal and financial considerations. At The Surrogacy Insider, we provide comprehensive guidance for those exploring this family-building option.